Both clinical and imaging characteristics are usually reversible if treated promptly. PRES frequently develops in the context of cytotoxic medication, sepsis, renal disease or autoimmune disorders. Early diagnosis of PRES, risk factors treatment, blood pressure lowering and convulsion control, are essential to ensure a full recovery of brain injury. We report a 14 - year - old boy who presented with seizures, blurred vision, and new hypertension after liver transplantation. Brain magnetic resonance imaging (MRI) was performed and showed the typical lesions of PRES syndrome. Symptoms fully recovered afterward. Clinicians should consider PRES in patients who develop acute neurological symptoms after solid organ transplantation.